A liquid biopsy test can safely detect as many as 26 undiagnosed cancers, according to a study of 9,900 women with no evidence or history of cancer. The findings show the test could be incorporated into routine clinical care in combination with conventional screening.
Overall, the blood test detected 26 cancers. While standard screening such as mammography or colonoscopy detected an additional 24 cancers. Together, screen-detected cancers (those detected through either blood testing or standard screening), accounted for more than half of the 96 cancers detected during the study period.
Diagnostic PET-CT most often localized cancers the new test detected. Surgeons could remove 12 of the cancers the blood test detected.
Researchers at the Ludwig Center at the Johns Hopkins Kimmel Cancer Center, who developed the blood test, say the study, called DETECT-A (Detecting cancers Earlier Through Elective mutation-based blood Collection and Testing) represents the first time researchers used any liquid biopsy blood test clinically to screen for cancer in a population without previously detected cancer for the purpose of diagnosis and intervention—specifically treatment with the intent to cure cancer.
At GivingTuesday.org:“We believe that generosity has the power to unite and heal communities in good times and bad. A global threat like COVID-19 touches every person on the planet, and it presents an opportunity to come together as a global community.”
“#GivingTuesdayNow is a new global day of giving and unity that will take place on May 5, 2020 – in addition to the regularly scheduled Dec 1, 2020 #GivingTuesday – as an emergency response to the unprecedented need caused by COVID-19.”
“Let’s come together to create a wave of generosity, citizen engagement, action from business and philanthropy, and support for communities and nonprofits around the world.”
For just $300 in parts, Rice University is devising an automated ApolloBVM device.
As we all know, there is a worldwide shortage of ventilators for those stricken with COVID-19. While there are finally multiple efforts underway to produce more ventilators, the time to and costs of converting factories has caused a real lag.
In the mean time, many innovative and entrepreneurial efforts are taking place.
“The ApolloBVM is a controllable, automated add-on solution to the existing and widely available Bag Valve Mask (BVM). The device compresses the BVM with a mechanical system that is able to provide consistent and accurate ventilation with positive-pressure.”
“This solution exists within the top range of high-acuity limited-operability (HALO) ventilator solutions with an a priori design to produce volume and pressure cycled ventilation that includes positive end-expiratory pressure (PEEP) and enriched oxygen sources.”
“The ApolloBVM is a rapidly scalable solution with a clinician-informed end-to-end design that repurposes the existing BVM global inventory toward widespread and safe access of hospital-grade mechanical ventilation.”
The video below highlights the promising, inexpensive, and simple-to-scale-up inhaler that would help those who are not in critical condition.
For much more information on this exciting project, click here.